High Street railway station serves High Street in Glasgow, Scotland and the surrounding area, which includes Townhead, the Merchant City, as well the western fringes of Dennistoun and Calton. The station is managed by ScotRail and is served by trains on the North Clyde Line. It is located in the eastern part of the city centre, with Strathclyde University, Glasgow Cathedral and Glasgow Royal Infirmary being major institutions located nearby.

The Merchant City, a new name introduced through urban renewal by the Scottish Development Agency and the city council in the 1980s is one part of the metropolitan central area of Glasgow. It commences at George Square and goes eastwards reaching Glasgow Cross, in the centre of Glasgow, Scotland. The eastern fringe of the Merchant City contains part of Glasgow's original medieval street plan, which stretches northwards towards neighbouring Townhead.