Highway 5 or the Trans-Samaria Highway, is one of Israel's main highways, connecting the Mediterranean coast immediately north of Tel Aviv with the central Sharon plain and eastwards to Ariel and other Israeli settlements in the northern West Bank.

Ariel is an Israeli settlement organized as a city council in the central West Bank, part of the Israeli-occupied territories, approximately 20 kilometres (12 mi) east of the Green Line and 34 kilometres (21 mi) west of the Jordan border. Ariel was first established in 1978 and its population was 20,520 in 2022, composed of veteran and young Israelis, English-speaking immigrants, and immigrants from the former Soviet Union, with an additional influx of above 10,000 students from Ariel University. It is the fourth largest Israeli settlement in the West Bank, after Modi'in Illit, Beitar Illit, and Ma'ale Adumim.