Hirado Castle was the seat of the Matsura clan, the daimyō of Hirado Domain, of Hizen Province, Kyūshū. It is located in present-day Hirado city Nagasaki Prefecture, Japan. It was also known as Kameoka Castle .

The Matsura clan, also spelled Matsuura, was a medieval and early modern Japanese samurai family who ruled Hirado Domain in Hizen Province on the island of Kyushu. They started as a group of military families under the name Matsura-to. They were involved in Toyotomi Hideyoshi's Kyushu campaign and the Japanese invasions of Korea. Around 1590, they built their seat, Hirado Castle. In 1871, the Meiji Restoration dissolved Japan's feudal lords, and the clan's final daimyo, Matsura Akira, was put into the kazoku class.