His Best Friend is a 1937 German crime film directed by and starring Harry Piel. It also features Edna Greyff, Henry Lorenzen and Lissy Arna. It was shot at the Johannisthal Studios in Berlin. The film's sets were designed by the art directors Karl Weber and Erich Zander. Piel had previously starred in a 1929 film of the same title.

Heinrich Piel, known professionally as Harry Piel, was a prolific German actor, film director, screenwriter, and film producer who was involved in over 150 films.