Historic Locust Grove is a 55-acre 18th-century farm site and National Historic Landmark situated in eastern Jefferson County, Kentucky in what is now Louisville. The site is owned by the Louisville Metro government, and operated as a historic interpretive site by Historic Locust Grove, Inc.

George Rogers Clark was an American military officer and surveyor from Virginia who became the highest-ranking Patriot military officer on the northwestern frontier during the Revolutionary War. He served as leader of the Virginia militia in Kentucky throughout much of the war. He is best known for his captures of Kaskaskia in 1778 and Vincennes in 1779 during the Illinois campaign, which greatly weakened British influence in the Northwest Territory and earned Clark the nickname of "Conqueror of the Old Northwest". The British ceded the entire Northwest Territory to the United States in the 1783 Treaty of Paris.