Hitoyoshi is a city in Kumamoto Prefecture, Japan. The city was founded on February 11, 1942. As of November 2022, the city has an estimated population of 30,752 and a population density of 144 per km2. The total area is 210.55 km2.

Kumamoto Prefecture is a prefecture of Japan located on the island of Kyūshū. Kumamoto Prefecture has a population of 1,748,134 and has a geographic area of 7,409 square kilometres (2,861 sq mi). Kumamoto Prefecture borders Fukuoka Prefecture to the north, Ōita Prefecture to the northeast, Miyazaki Prefecture to the southeast, and Kagoshima Prefecture to the south.