Holdrege is a city in Phelps County, Nebraska, United States. The population was 5,495 at the 2010 census. It is the county seat of Phelps County. The Nebraska Prairie Museum is located in Holdrege.

Phelps County is a county in the U.S. state of Nebraska. As of the 2020 United States Census, the population was 8,968. Its county seat is Holdrege. The county was formed in 1873, and was named for William Phelps (1808–1889), a steamboat captain and early settler.