Hollis is a station on the Long Island Rail Road's Main Line at the intersection of 193rd Street and Woodhull Avenue in the Hollis neighborhood of Queens, New York City. With a few exceptions, only trains on the Hempstead Branch stop here.

The Main Line is a rail line owned and operated by the Long Island Rail Road in the U.S. state of New York. It begins as a two-track line at Long Island City station in Long Island City, Queens, and runs along the middle of Long Island about 95 miles (153 km) to Greenport station in Greenport, Suffolk County. At Harold Interlocking approximately one mile east of Long Island City, the tracks from the East River Tunnels and 63rd Street Tunnel into Manhattan intersect with the Main Line, which most trains use rather than using the Long Island City station.