Holly Hill is a city in Volusia County, Florida, United States. Holly Hill's city limits lie entirely on the Florida mainland, unlike the larger cities on either side of it, Daytona Beach and Ormond Beach, which encompass both the mainland and the beachfront barrier island across the Halifax River. The population was 12,958 at the 2020 census.

Volusia County is located in the east-central part of the U.S. state of Florida between the St. Johns River and the Atlantic Ocean. As of the 2020 census, the county was home to 553,543 people, an increase of 11.9% from the 2010 census. It was founded on December 29, 1854, from part of Orange County, and was named for the community of Volusia, located in northwestern Volusia County. Its first county seat was Enterprise. Since 1887, its county seat has been DeLand.