Holme is a village and civil parish in Cambridgeshire, England. Holme lies approximately 7 miles (11 km) south of Peterborough, near Conington and Yaxley. Holme is situated within Huntingdonshire which is a non-metropolitan district of Cambridgeshire as well as being a historic county of England. The parish contains the lowest point in Great Britain, 2.75 metres (9.0 ft) below sea level.

Huntingdonshire is a local government district in Cambridgeshire, England, which was historically a county in its own right. It borders Peterborough to the north, Fenland to the north-east, East Cambridgeshire to the east, South Cambridgeshire to the south-east, Central Bedfordshire and Bedford to the south-west, and North Northamptonshire to the west.