"Holy Key" is a hip hop single by American musician DJ Khaled, featuring American rappers Big Sean, Kendrick Lamar and American singer Betty Wright. It was released on July 22, 2016, by We the Best Music Group and Epic Records as the third single of DJ Khaled's ninth studio album, Major Key. The song was produced by Cool & Dre.

Bessie Regina Norris, better known by her stage name Betty Wright, was an American soul and R&B singer, songwriter and background vocalist. Beginning her professional career in the late 1960s as a teenager, Wright rose to fame in the 1970s with hits such as "Clean Up Woman" and "Tonight Is the Night". Wright was also prominent in her use of whistle register.