Holy Trinity Church, Headington Quarry, is located in the district of Headington Quarry, Oxford, England. It is an active Anglican parish church in the Diocese of Oxford.

Headington Quarry is a residential district of Oxford, England, located east of Headington and west of Risinghurst, just inside the Oxford ring road in the east of the city. To the south is Wood Farm. Today the district is also known colloquially as "Quarry". The area, now residential, is considerably uneven due to previous quarrying in the area.