The relationship between religion and homosexuality has varied greatly across time and place, within and between different religions and denominations, with regard to different forms of homosexuality and bisexuality. The present-day doctrines of the world's major religions and their denominations differ in their attitudes toward these sexual orientations. Adherence to anti-gay religious beliefs and communities is correlated with the prevalence of emotional distress and suicidality in sexual minority individuals, and is a primary motivation for seeking conversion therapy.

In the Abrahamic religions, Sodom and Gomorrah were two cities destroyed by God for their wickedness. Their story parallels the Genesis flood narrative in its theme of God's anger provoked by man's sin. They are mentioned frequently in the prophets and the New Testament as symbols of human wickedness and divine retribution, and the Quran also contains a version of the story about the two cities.