The Honeywell 316 was a popular 16-bit minicomputer built by Honeywell starting in 1969. It is part of the Series 16, which includes the Models 116, 316 (1969), 416 (1966), 516 (1966) and DDP-716 (1969). They were commonly used for data acquisition and control, remote message concentration, clinical laboratory systems, Remote Job Entry and time-sharing. The Series-16 computers are all based on the DDP-116 designed by Gardner Hendrie at Computer Control Company, Inc. (3C) in 1964.

A minicomputer, or colloquially mini, is a type of smaller general-purpose computer developed in the mid-1960s and sold at a much lower price than mainframe and mid-size computers from IBM and its direct competitors. In a 1970 survey, The New York Times suggested a consensus definition of a minicomputer as a machine costing less than US$25,000, with an input-output device such as a teleprinter and at least four thousand words of memory, that is capable of running programs in a higher level language, such as Fortran or BASIC.