Horatio Walpole, 1st Baron Walpole, was an English diplomat, politician and peer who served as the British ambassador to France from 1724 to 1730. He was the son of Robert Walpole and the younger brother of Robert Walpole, the first Prime Minister of Great Britain.

Sir Edward Walpole KB PC (Ire) was a British politician, and a younger son of Sir Robert Walpole, Prime Minister from 1721 to 1742.