House of Cards is a 1968 American neo-noir crime film directed by John Guillermin and starring George Peppard, Inger Stevens, and Orson Welles. Filmed in France and Italy, it marked the third time that Peppard and Guillermin worked together.

John Guillermin was a French-British film director, writer and producer who was most active in big-budget, action-adventure films throughout his lengthy career.