The Howrah–Prayagraj–Mumbai line, is a railway line connecting Kolkata and Mumbai via Prayagraj. The 2,160-kilometre long (1,340 mi) railway line was opened to traffic in 1870. This railway line was 2,146-kilometre long (1,333 mi) until 2004. In 2004 the construction of Indira Sagar Dam submerged the old alignment near Khandwa & a new alignment of 14-kilometre long (8.7 mi) was relaid.

Khandwa is a city and a nagar nigam in the Nimar region of Madhya Pradesh, India. It is the administrative headquarters of the Khandwa district, formerly known as East Nimar District.