The Huexotzinco Codex or Huejotzingo Codex is a colonial-era Nahua pictorial manuscript, one of the group of manuscripts collectively known as Aztec codices. It is an eight-sheet document on amatl, a pre-European paper made in Mesoamerica, and consists of part of the testimony in a legal case against members of the First Audiencia in Mexico, particularly its president, Nuño de Guzmán, ten years after the 1521 Spanish conquest.

Aztec codices are Mesoamerican manuscripts made by the pre-Columbian Aztec, and their Nahuatl-speaking descendants during the colonial period in Mexico.