Humboldt is a city in Gibson and Madison counties, Tennessee. The population was 8,452 at the 2010 census, a decline of 1,015 from 2000. It is the principal city of and is included in the Humboldt, Tennessee Micropolitan Statistical Area, which is included in the Jackson, Tennessee-Humboldt, Tennessee Combined Statistical Area.

Gibson County is a county located in the U.S. state of Tennessee. As of the 2020 census, the population was 50,429. Its county seat is Trenton. The county was formed in 1823 and named for John H. Gibson, a soldier of the Natchez Expedition and the Creek War.