Hurricane Isabel was the strongest Atlantic hurricane since Mitch, and the deadliest, costliest, and most intense hurricane in the 2003 Atlantic hurricane season. Hurricane Isabel was also the strongest hurricane in the open waters of the Atlantic, both by wind speed and central pressure, before being surpassed by hurricanes Irma and Dorian in 2017 and 2019, respectively. The ninth named storm, fifth hurricane, and second major hurricane of the season, Isabel formed near the Cape Verde Islands from a tropical wave on September 6, in the tropical Atlantic Ocean. It moved northwestward, and within an environment of light wind shear and warm waters, it steadily strengthened to reach peak winds of 165 mph (266 km/h) on September 11. After fluctuating in intensity for four days, during which it displayed annular characteristics, Isabel gradually weakened and made landfall on the Outer Banks of North Carolina, with winds of 105 mph (169 km/h) on September 18. Isabel quickly weakened over land and became extratropical over western Pennsylvania on the next day. On September 20, the extratropical remnants of Isabel were absorbed into another system over Eastern Canada.

The Outer Banks are a 200 mi (320 km) string of barrier islands and spits off the coast of North Carolina and southeastern Virginia, on the east coast of the United States. They line most of the North Carolina coastline, separating Currituck Sound, Albemarle Sound, and Pamlico Sound from the Atlantic Ocean. A major tourist destination, the Outer Banks are known for their wide expanse of open beachfront and the Cape Hatteras National Seashore. The seashore and surrounding ecosystem are important biodiversity zones, including beach grasses and shrubland that help maintain the form of the land.