"Hustler's Ambition" is a song by American rapper 50 Cent. Written by 50 Cent and produced by B-Money "B$", the song was released as the first single from the soundtrack to the film Get Rich or Die Tryin' (2005). Built around a soul–influenced production sampling the Frankie Beverly and Maze song "I Need You", "Hustler's Ambition" features lyrics regarding 50 Cent's rise to fortune and fame, intended to mirror the experience faced by 50 Cent's character in the film: it marks a shift from influence of hardcore hip hop present in 50 Cent's earlier work. "Hustler's Ambition" was released to digital retailers in the United States in October 2005 via Interscope Records, with a CD release following in February 2006.

Get Rich or Die Tryin': Music from and Inspired by the Motion Picture is the soundtrack to the 2005 film of the same name, released on November 8, 2005, on Interscope Records and 50 Cent's G-Unit Records. It features artists on the G-Unit label such as 50 Cent, Lloyd Banks, Young Buck, Tony Yayo, Olivia, and Mobb Deep. The album sold 320,000 copies in the first week, debuting behind country singer Kenny Chesney's The Road and the Radio. In December 2005, the RIAA certified the album Platinum. To date, the album has sold over three million copies worldwide.