Hyatt Regency Chennai is an 18-storey five-star luxury hotel located on Anna Salai at Teynampet in Chennai, India. Designed in 1986, the construction of the hotel started in the 1990s. However, the completion was delayed for nearly two decades and the hotel was opened on 10 August 2011 at a cost of ₹5.50 billion. Built on 18,510 square metres (199,200 sq ft) of land, it is the first Hyatt hotel in South India and has 327 rooms.

Anna Salai, formerly known as St. Thomas Mount Road or simply Mount Road, is an arterial road in Chennai, India. It starts at the Cooum Creek, south of Fort St George, leading in a south-westerly direction towards St. Thomas Mount, and ends at the Kathipara Junction in Guindy. Beyond the Kathipara Junction, a branch road arises traversing westwards to Poonamallee to form the Mount-Poonamallee Road while the main branch continuing southwards to Chennai Airport, Tambaram and beyond to form Grand Southern Trunk Road. Anna Salai, which is more than 400 years old, is acknowledged as the most important road in Chennai city. The head offices of many commercial enterprises and public buildings are located along Anna Salai. It is the second longest road in Chennai, after EVR Periyar Salai.