A hypocenter or hypocentre, also called ground zero or surface zero, is the point on the Earth's surface directly below a nuclear explosion, meteor air burst, or other mid-air explosion. In seismology, a hypocenter of an earthquake is its point of origin below ground; a synonym is the focus of an earthquake.

A nuclear explosion is an explosion that occurs as a result of the rapid release of energy from a high-speed nuclear reaction. The driving reaction may be nuclear fission or nuclear fusion or a multi-stage cascading combination of the two, though to date all fusion-based weapons have used a fission device to initiate fusion, and a pure fusion weapon remains a hypothetical device. Nuclear explosions are used in nuclear weapons and nuclear testing.