IBM Power microprocessors are designed and sold by IBM for servers and supercomputers. The name "POWER" was originally presented as an acronym for "Performance Optimization With Enhanced RISC". The Power line of microprocessors has been used in IBM's RS/6000, AS/400, pSeries, iSeries, System p, System i, and Power Systems lines of servers and supercomputers. They have also been used in data storage devices and workstations by IBM and by other server manufacturers like Bull and Hitachi.

The RISC System/6000 (RS/6000) is a family of RISC-based Unix servers, workstations and supercomputers made by IBM in the 1990s. The RS/6000 family replaced the IBM RT PC computer platform in February 1990 and was the first computer line to see the use of IBM's POWER and PowerPC based microprocessors. In October 2000, the RS/6000 brand was retired for POWER-based servers and replaced by the eServer pSeries. Workstations continued under the RS/6000 brand until 2002, when new POWER-based workstations were released under the IntelliStation POWER brand.