Ignacia del Espíritu Santo luco, also known as "Mother Ignacia" was a Filipino religious sister of the Catholic Church. She was known for her acts of piety and religious poverty and founded the Congregation of the Sisters of the Religious of the Virgin Mary, the first native Filipino female congregation with approved pontifical status in what is now the Republic of the Philippines.

The Congregation of the Religious of the Virgin Mary (Spanish: Religiosas de la Beata Virgen María, abbreviated RVM, is a Roman Catholic centralized religious institute of consecrated life of Pontifical Right for women founded in Manila in 1684 by the Filipina Venerable Mother Ignacia del Espíritu Santo.