The illegal drug trade, drug trafficking, or narcotrafficking is a global black market dedicated to the cultivation, manufacture, distribution and sale of prohibited drugs. Most jurisdictions prohibit trade, except under license, of many types of drugs through the use of drug prohibition laws. The think tank Global Financial Integrity's Transnational Crime and the Developing World report estimates the size of the global illicit drug market between US$426 and US$652 billion in 2014 alone. With a world GDP of US$78 trillion in the same year, the illegal drug trade may be estimated as nearly 1% of total global trade. Consumption of illegal drugs is widespread globally, and it remains very difficult for local authorities to reduce the rates of drug consumption.

The 'Ndrangheta is an Italian Mafia-type association based in the peninsular region of Calabria and dating back to the 19th century. Although loosely structured, it is considered one of the most powerful organized crime groups in the world. It is characterized by a horizontal structure made up of autonomous clans known as 'ndrine, based almost exclusively on blood ties. Since the 1950s, following wide-scale emigration from Calabria, 'Ndrangheta clans dispersed to other European countries, Australia and the Americas. Currently, its main activity is drug trafficking, but it also deals with arms trafficking, money laundering, racketeering, extortion, and loan sharking.