Illinois Route 16 is an east–west highway in central Illinois. Its western terminus is at the Joe Page Bridge over the Illinois River in Hardin, while its eastern terminus is at Paris at Illinois Route 1 and U.S. Route 150, with Illinois Route 133. This is a distance of 174.66 miles (281.09 km).

Paris is a city in Edgar County, Illinois, 165 miles (266 km) south of Chicago and 90 miles (140 km) west of Indianapolis. The population was 8,291 at the 2020 census. It is the county seat and largest city of Edgar County.