Immovable Cultural Heritage of Great Importance are those objects of Immovable cultural heritage that enjoy the second-highest level of state protection in the Republic of Serbia, behind the Immovable Cultural Heritage of Exceptional Importance. Immovable Cultural Heritage is classified as being of Great Importance upon decision by the National Assembly of Serbia. They are inscribed in the Central Register of Immovable cultural property maintained by the Institute for the Protection of Cultural Monuments of Serbia. Objects of Immovable cultural heritage have to fulfill one or more of those criteria defined in the Law on Cultural Heritage of 1994 in order to be categorized as being "of great importance":importance for a certain area or time-span; evidence of social or natural development, or the socio-economic and cultural-historic development conditions during a certain time-span; evidence about important historic events or persons from the national history.

Cultural heritage of Serbia represents the totality of national cultural heritage in Serbia as defined by Serbia's Law on Cultural Goods. Some of national heritage sites in Serbia are also World Heritage Sites.