Immunoglobulin superfamily
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The immunoglobulin superfamily is a large protein superfamily of cell surface and soluble proteins that are involved in the recognition, binding, or adhesion processes of cells. Molecules are categori
Antibody in complex with hen egg white lysozyme.
The major histocompatibility complex is a large locus on vertebrate DNA containing a set of closely linked polymorphic genes that code for cell surface proteins essential for the adaptive immune syste
Immunoglobulin superfamily
…domains in the extracellular portion; one IgV domain at the N-terminus and one IgC1 domain adjacent to the cell membrane. Antigen presenting molecules Class I MHC Class II MHC beta-2 microglobulin The ligands for TCRs are major histocompatibility complex (MHC) proteins. These come in two forms; MHC class I forms…
Major histocompatibility complex protein (class I) in orange and pink, with a presented peptide in red. Membrane in grey. The transmembrane and cytoplasmic domains are shown in cartoon form. (PDB: 1hsa)
Schematic view of MHC class I and MHC class II molecules
T-cell receptor complexed with MHC-I and MHC-II