Impasto is a technique used in painting, where paint is laid on an area of the surface in thick layers thick enough that the brush or painting-knife strokes are visible. Paint can be mixed right on the canvas; when dry, impasto provides texture. The word impasto is Italian in origin. Italian usage of "impasto" includes a potting technique. According to Webster's New World College Dictionary, the root noun of impasto is pasta, whose primary meaning in Italian is paste. Oil paint is the traditional medium for impasto painting, due to its thick consistency and slow drying time. Acrylic paint can be used for impasto by adding heavy body acrylic gels. Impasto is not seen done in watercolor or tempera without the addition of thickening agent due to the inherent thinness of these media. An artist working in pastels can produce a limited impasto effect by pressing a soft pastel against the paper; the impasto technique serves several purposes. First, it makes the light reflect in a particular way, giving the artist additional control over the play of light in the painting.

Second, it can add expressiveness to the painting, with the viewer being able to notice the strength and speed by which the artist applied the paint. Third, impasto can push a piece from a painting to a three-dimensional sculptural rendering; the first objective was sought by masters such as Rembrandt and Vermeer, to represent folds in clothes or jewels: it was juxtaposed with a more delicate painting style. Much the French Impressionists created pieces covering entire canvases with rich impasto textures. Vincent van Gogh used it for aesthetics and expression. Abstract expressionists such as Hans Hofmann and Willem de Kooning made extensive use of it, motivated in part by a desire to create paintings which record the action of painting itself. Still more Frank Auerbach has used such heavy impasto that some of his paintings become nearly three-dimensional. Impasto gives texture to the painting, meaning it can be opposed to more flat, smooth, or blended painting styles. Many artists have used the impasto technique.

Some of the more notable ones including: Rembrandt van Rijn, Diego Velázquez, Vincent van Gogh, Jackson Pollock, Willem de Kooning. Selected examples of paintings which make use of the impasto technique Media related to Impasto at Wikimedia Commons Lindberg, Ted. Alfred Currier: Impasto National Portrait Gallery, London. Impasto Tate Britain Gallery, London. Frank Auerbach, Bacchus & Ariadne

Flora Stone Mather was a prominent philanthropist and advocate supporting religious, social welfare and educational institutions in Cleveland, Ohio. Her leadership and generosity, directed toward promoting the education of women, led to Western Reserve University's College for Women being renamed in 1931 as the Flora Stone Mather College for Women. Flora Amelia Stone was born on April 1852 in Cleveland, Ohio, her father was Amasa Stone and her mother was Julia Gleason Stone. Amasa Stone was a wealthy builder of railroads and bridges, she had two siblings, a brother, Adelbert Barnes Stone, a geology student at Yale University, who died while swimming in the Connecticut River, a sister, Clara Stone Hay. Flora Stone graduated from the Cleveland Academy in 1875. In spite of her family's privileged position and interest in assuring her brother's elite college education, she did not attend college. There was not a value placed on post-secondary education for the two Stone daughters. In 1881 Flora married Samuel Livingston Mather, a wealthy businessman with shipping and mining interests in the Great Lakes region.

The couple had four children: Samuel Livingston, Amasa Stone and Philip Richard. Flora Stone Mather's philanthropy and devotion to civic causes was rooted in the experience of her family's strong Christian faith and their active membership in the city's Old Stone Church. Notable Cleveland social welfare institutions that were beneficiaries of her financial gifts include two settlement houses, Goodrich House and Hiram House, the Legal Aid Society of Cleveland, Consumers League of Ohio and the Cleveland Day Nursery and Kindergarten Association, her engagement with these organizations went well beyond financial support, involving her in direct service and advocacy for broader charitable investment in the work. Much of her philanthropy was directed to educational institutions like Adelbert College, Western Reserve University's College for Women, Hathaway Brown School and Lakeside Hospital School of Nursing, named in her honor, her sister, Clara Stone Hay, was married to the wealthy statesman John Hay.

Together and Clara continued their parents’ tradition of civic generosity, earning their own recognition as prominent philanthropists. Flora Mather's most enduring philanthropic legacy is woven into Case Western Reserve University's past and present, her family was among the university's earliest benefactors. Amasa Stone, her father, was instrumental in moving Western Reserve College from Hudson, Ohio to Cleveland in 1882. In that year he made a substantial donation to the college and its undergraduate division was renamed'Adelbert College' in honor of his son. Amasa Stone died the following year, but his support for the college was continued by his daughters and sons-in-law. In 1892 Flora Mather donated generously to a fledgling effort to reestablish coeducation at Western Reserve College. Uproar over the college's controversial decision to end the admission of women led to the creation of a small separate women's division known as the College for Women. Flora's sister and brother-in-law became the new college's first significant benefactors.

Flora soon became a source of continuing support for the college. Her generosity and enthusiastic engagement in the life of the school was recognized as so crucial to reestablishing coeducation in the city's leading educational institution, that in 1931 the college was renamed in her honor as the Flora Stone Mather College for Women; the women's college was integrated into the growing Western Reserve University. The Flora Stone Mather Quadrangle, known to students as the Mather Quad, is the heart of Case Western Reserve University's campus, it is the location of the Kelvin Smith Library, Thwing Student Center, School of Law, Mandel School of Applied Social Sciences, Weatherhead School of Management and many departments of the College of Arts and Sciences. Scattered around the campus are buildings funded by the Stone and Hay families, some still bearing the Mather name in dedication to Flora Stone Mather; the university's Amasa Stone Chapel was given in memory of their father by Flora Mather and Cora Hay.

A portion of the campus has been designated as the Flora Stone Mather College Historic District. Flora Stone Mather died on January 19, 1909 at ‘Shoreby’, the family's home on the Lake Erie shore in Bratenahl near downtown Cleveland, she is buried along with other family members in Lake View Cemetery in Cleveland. Her Fathers’ Daughter: Flora Stone Mather and Her Gifts to Cleveland Retrieved May 7, 2016 Flora Stone Mather: Daughter of Cleveland's Euclid Avenue & Ohio's Western Reserve, by Gladys Haddad, November May 7, 2016 WRUW-FM, The Flora Stone Mather Radio Club Retrieved May 6, 2016 The Schools of Case Western University, University Archives Retrieved May 7, 2016 A Legacy of Stewardship: Flora Stone Mather Retrieved May 7, 2016

The Alvear Palace Hotel is a luxury hotel located in Avenida Alvear in Recoleta, an upscale neighbourhood in Buenos Aires, Argentina. The hotel was inaugurated in 1932 and, following extensive refurbishment, was reinaugurated in 1994; the hotel was built by Buenos Aires businessman and socialite Dr. Rafael de Miero, to Paris in the early 1920s and wanted to bring some of that Belle Epoque grandeur to his flourishing hometown, he bought and demolished a large house on the corner of Avenida Alvear and Ayacucho in 1922, which began the decade-long on-again, off-again project, which opened in 1932. A success, consuming another old mansion on Avenida Alvear. In 1970, ownership passed to the 26-year-old Andreas von Salm-Kyrburg Wernitz, Duke of Hornes, Spanish cousin of King Juan Carlos I, who presided over the hotel's slow decline as a result of labour disputes and a general Argentinian economic stagnation. With bankruptcy threatening, in 1978 Wernitz sold the hotel to the Aragon Hotel Group, since 1984, it's been part of David Sutton Dabbah's Alvear Luxury Hotels.

It was renovated in 1984, again in 2004. In 1962 the actor Tony Curtis and his family stayed in room 606. In 1964 in room 805, the actress Juliette Mayniel tried to commit suicide, when she learned that her husband Vittorio Gassman was deceiving her. A hotel employee saved her just in time. On May 4, 1992, the Swedish music group Roxette recorded the songs "Here Comes the Weekend" and "So Far Away" in the room 603, which were included in the album TourismHoracio Ferrer Lived in hotel for 38 years till his death in 2014. In 2009 the hotel was featured in the movie Walt & El Grupo, when Walt Disney come to South America in 1942. Evans, Polly. "My kind of town: Buenos Aires". Daily Telegraph. London. Retrieved 2008-10-06. "EN EL ALVEAR PALACE HOTEL MEDIA TARDE. EL CHEF PATISSIER RICARDO BASCONCELLOS COMPARTE SUS DELICIAS PARA UN ENCUENTRO EXQUISITO CON FAMILIARES Y AMIGOS. SENCILLEZ Y SOFISTICACIÓN AL MISMO TIEMPO, UN MIX IRRESISTIBLE". Rio Negro. Archived from the original on 2008-10-08. Retrieved 2008-10-06.

Alvaer Palace Hotel Site

NADH dehydrogenase iron-sulfur protein 4, mitochondrial known as NADH-ubiquinone oxidoreductase 18 kDa subunit is an enzyme that in humans is encoded by the NDUFS4 gene. This gene encodes an nuclear-encoded accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase. Complex I passes them to the electron acceptor ubiquinone. Mutations in this gene can cause mitochondrial complex I deficiencies such as Leigh syndrome. NDUFS4 has 8 exons; the NDUFS4 gene produces a 20.1 kDa protein composed of 175 amino acids. NDUFS4, the protein encoded by this gene, is a member of the complex I NDUFS4 subunit family, it is a peripheral membrane protein located on the matrix side of the inner mitochondrial membrane. NDUFS4 is a component of the iron-sulfur fragment of the enzyme and contains a transit peptide domain, 4 turns, 6 beta strands, 4 alpha helixes. Alternative splicing results in multiple transcript variants. Complex I, or NADH:ubiquinone oxidoreductase, the first multisubunit enzyme complex of the mitochondrial respiratory chain, plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells.

It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. Mutations in the NDUFS4 gene are associated with Mitochondrial Complex I Deficiency, autosomal recessive; this deficiency is the most common enzymatic defect of the oxidative phosphorylation disorders. Mitochondrial complex I deficiency shows extreme genetic heterogeneity and can be caused by mutation in nuclear-encoded genes or in mitochondrial-encoded genes. There are no obvious genotype-phenotype correlations, inference of the underlying basis from the clinical or biochemical presentation is difficult, if not impossible. However, the majority of cases are caused by mutations in nuclear-encoded genes.

It causes a wide range of clinical disorders, ranging from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, nonspecific encephalopathy, hypertrophic cardiomyopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, some forms of Parkinson disease. Complex I deficiency with autosomal recessive inheritance results from mutation in nuclear-encoded subunit genes, including NDUFV1, NDUFV2, NDUFS1, NDUFS2, NDUFS3, NDUFS6, NDUFS7, NDUFS8, NDUFA2, NDUFA11, NDUFAF3, NDUFAF10, NDUFB3, NDUFB9, ACAD9, FOXRED1, MTFMT. NDUFS4 has been shown to have 58 binary protein-protein interactions including 57 co-complex interactions. NDUFS4 appears to interact with UBE2G2; this article incorporates text from the United States National Library of Medicine, in the public domain

Dolly Kitty Aur Woh Chamakte Sitare is an upcoming Indian comedy satire Hindi film starring Konkona Sen Sharma and Bhumi Pednekar. The film is directed by Alankrita Shrivastava and is produced by Ekta Kapoor and Shobha Kapoor under their banner Balaji Telefilms.. The film features young actors Vikrant Massey and Amol Parashar in prominent roles opposite the leading ladies; the film premiered at the 24th Busan International Film Festival under the section'A Window on Asian Cinema' on 4 October 2019. The story of the film revolves around about a secret shared by them. Living in the suburbs of New Delhi, Dolly is a middle-class working mother with a son and a hardworking husband, they are excited. There is a secret. Kazal moves from rural India to live in a city, but the opportunities are few for a young woman with little skills. So she meets a man. Now the two cousins who were critical of each other’s life, share their secrets and understand each other. Konkona Sen Sharma as Dolly Bhumi Pednekar as Kitty Amol Parashar Kubra Sait Karan Kundra as DJ Johny Vikrant Massey Mushtaq Khan In an interview with Kovid Gupta, Shrivastava mentioned that she wrote the first draft of the film while completing post-production on Lipstick Under My BurkhaThe first look of the film was released on 15 October 2018 by producer Kapoor on her Twitter account.

The principal photography of the film began on 15 October 2018. Dolly Kitty Aur Woh Chamakte Sitare on IMDb Dolly Kitty Aur Woh Chamakte Sitare on Bollywood Hungama Balaji Telefilms official site Template:2020s-Hindi-film-stub

The large-headed whiting, Sillago megacephalus, is a dubious species of coastal marine fish in the smelt-whiting family that has only been recorded from one specimen captured off the coast of China in 1933. Although similar to Sillago sihama, the species is characterised by an unusually large head which accounts for 33% of the total body length; the large-headed whiting is one of 29 species in the genus Sillago, one of three divisions of the smelt whiting family Sillaginidae. The smelt-whitings are Perciformes in the suborder Percoidei; the only specimen of the species recorded was taken from Paoping Harbour in Hainan, China in 1933. Lin recorded the new species. In preparation of a 1985 review of the sillaginids, Roland McKay was unable to locate the holotype and has presumed it to be lost. McKay noted that based on its description, all features except an unusually large head where characteristic of the common species Sillago sihama, suggesting the S. megacephalus is a junior synonym of S. sihama.

The common name of'large-headed whiting' is a straight translation from its binomial name, signifying the diagnostic head length. As noted, the large-headed whiting is similar to Sillago sihama, but has a head length, 33% of the body length, compared to the 27-30% observed in S. sihama. The first dorsal fin has 11 spines, while the second dorsal fin has 22 soft rays; the anal fin is similar with 23 soft rays. There are about 70 lateral line scales; the colour is uniform all with only the tip of the spinous dorsal fins black. Little else is known, including vertebrae numbers; the specimen described was 158 mm in length. The only known specimen of large-headed whiting was taken from Taiwanese waters, with no other records known of, no information of the habitat or depth the species lives at available. Aspects of the species biology and importance to fisheries are unknown at the present. Large-headed whiting at Fishbase