In-system programming (ISP), or also called in-circuit serial programming (ICSP), is the ability of some programmable logic devices, microcontrollers, chipsets and other embedded devices to be programmed while installed in a complete system, rather than requiring the chip to be programmed prior to installing it into the system. It also allows firmware updates to be delivered to the on-chip memory of microcontrollers and related processors without requiring specialist programming circuitry on the circuit board, and simplifies design work.

A microcontroller or microcontroller unit (MCU) is a small computer on a single integrated circuit. A microcontroller contains one or more CPUs along with memory and programmable input/output peripherals. Program memory in the form of NOR flash, OTP ROM or ferroelectric RAM is also often included on chip, as well as a small amount of RAM. Microcontrollers are designed for embedded applications, in contrast to the microprocessors used in personal computers or other general purpose applications consisting of various discrete chips.