Independence is a home rule-class city in Kenton County, Kentucky, United States. It is one of its county's two seats of government. The population was 28,676 at the time of the 2020 census. It is the third largest city in Northern Kentucky after Covington and Florence, and is part of the Cincinnati metropolitan area.

Kenton County is a county located in the northern part of the Commonwealth of Kentucky. As of the 2020 census, the population was 169,064, making it the third most populous county in Kentucky. Its county seats are Covington and Independence. It was, until November 24, 2010, the only county in Kentucky to have two legally recognized county seats. The county was formed in 1840 and is named for Simon Kenton, a frontiersman notable in the early history of the state.