The Indian River Lagoon is a grouping of three lagoons: the Mosquito Lagoon, the Banana River, and the Indian River, on the Atlantic Coast of Florida; one of the most biodiverse estuaries in the Northern Hemisphere and is home to more than 4,300 species of plants and animals.

Lake Okeechobee is the largest freshwater lake in the U.S. state of Florida. It is the tenth-largest natural freshwater lake among the 50 states of the United States and the second-largest natural freshwater lake contained entirely within the contiguous 48 states, after Lake Michigan.