The Indiana Toll Road, officially the Indiana East–West Toll Road, is a controlled-access toll road that runs for 156.28 miles (251.51 km) east–west across northern Indiana from the Illinois state line to the Ohio state line. It has been advertised as the "Main Street of the Midwest". The entire toll road is designated as part of Interstate 90 (I-90), and the segment from Lake Station east to the Ohio state line is a concurrency with I-80. The toll road is owned by the Indiana Finance Authority and operated by the Indiana Toll Road Concession Company (ITRCC), which is owned by IFM Investors.

Interstate 90 (I-90) in the US state of Illinois runs roughly northwest-to-southeast through the northern part of the state. From the Wisconsin state line at South Beloit, it heads south to Rockford before heading east-southeast to the Indiana state line at Chicago. I-90 traverses 124 miles (200 km) through a variety of settings, from farmland west of the Fox River Valley through the medium-density suburbs west of O'Hare International Airport, through Downtown Chicago, and through the heart of the industrial southeast side of Chicago before entering Indiana.