Indiana University–Purdue University Indianapolis, commonly referred to as IUPUI, is a public research university in Indianapolis, Indiana, United States. It is a collaboration between Indiana University and Purdue University that offers undergraduate, graduate, and professional degrees from both universities. Administered primarily through Indiana University as a core campus and secondarily through Purdue University as a regional campus, it is Indiana's primary urban research and academic health sciences institution. IUPUI is located in downtown Indianapolis along the White River and Fall Creek.

Indianapolis, colloquially known as Indy, is the capital and most populous city of the U.S. state of Indiana and the seat of Marion County. Located in Central Indiana, the city lies along the White River's West Fork near its confluence with Fall Creek. Indianapolis's official slogan, "Crossroads of America", reflects the city's central location relative to other major North American markets and its historic importance as a transportation hub.