The Indianapolis 500, formally known as the Indianapolis 500-Mile Race, and commonly called the Indy 500, is an annual automobile race held at Indianapolis Motor Speedway (IMS) in Speedway, Indiana, United States, an enclave suburb of Indianapolis. The event is traditionally held over Memorial Day weekend, usually the last weekend of May. It is contested as part of the IndyCar Series, the top level of American open-wheel car racing, a formula colloquially known as "Indy car racing". The track itself is nicknamed the "Brickyard", as the racing surface was paved in brick in the fall of 1909. One yard of brick remains exposed at the start/finish line. The event, billed as The Greatest Spectacle in Racing, is considered part of the Triple Crown of Motorsport along with the 24 Hours of Le Mans and the Monaco Grand Prix, with which it typically shares a date.

The IndyCar Series, currently known as the NTT IndyCar Series under sponsorship, is the highest class of American open-wheel car racing in the United States, which has been conducted under the auspices of various sanctioning bodies since 1920 after two initial attempts in 1905 and 1916. The series is self-sanctioned by its parent company, IndyCar, LLC., which began in 1996 as the Indy Racing League (IRL) and was created by then Indianapolis Motor Speedway owner Tony George as a competitor to Championship Auto Racing Teams (CART). In 2008, the IndyCar Series merged with CART's successor, the Champ Car World Series and the history and statistics of both series, as well as those from its predecessors, were unified.