The Indo-Parthian Kingdom was a Parthian kingdom founded by Gondophares, and active from 19 CE to c. 226 CE. At their zenith, they ruled an area covering parts of eastern Iran, various parts of Afghanistan and the northwest regions of the Indian subcontinent. The rulers may have been members of the House of Suren, and the kingdom has even been called the "Suren Kingdom" by some authors.

Gondophares I was the founder of the Indo-Parthian Kingdom and its most prominent king, ruling from 19 to 46. He probably belonged to a line of local princes who had governed the Parthian province of Drangiana since its disruption by the Indo-Scythians in c. 129 BC, and may have been a member of the House of Suren. During his reign, his kingdom became independent from Parthian authority and was transformed into an empire, which encompassed Drangiana, Arachosia, and Gandhara. He is generally known from the Acts of Thomas, the Takht-i-Bahi inscription, and silver and copper coins bearing his visage.