Infestation 2 is a crossover event that was published by IDW Publishing from January to April 2012. Serving as the sequel to Infestation, it consisted of two book-end one-shots, and two-issue limited series from The Transformers, Dungeons & Dragons, Teenage Mutant Ninja Turtles, G.I. Joe and 30 Days of Night.

IDW Publishing is an American publisher of comic books, graphic novels, art books, and comic strip collections. It was founded in 1999 as the publishing division of Idea and Design Works, LLC (IDW) and is recognized as the fifth-largest comic book publisher in the United States, behind Marvel, DC, Dark Horse, and Image Comics, ahead of other comic book publishers such as Archie, Boom!, Dynamite, Valiant, and Oni Press. The company is known for its licensed comic book adaptations of films, television shows, video games, and cartoons.