The Inter American University of Puerto Rico is a private Christian university with its main campus in San Germán, Puerto Rico. It also has campuses in Aguadilla, Arecibo, Barranquitas, Bayamón, Fajardo, Guayama, Ponce, and San Juan. The university also has three professional schools: School of Optometry, School of Law, and the School of Aeronautics. The Inter offers academic programs in 11 teaching units. It was founded in San Germán in 1912. The San Germán campus is also the home to the Inter American School, a private co-educational college-preparatory school.

San Germán is a historic town and municipality located in the Sabana Grande Valley of southwestern region of Puerto Rico, south of Mayagüez and Maricao, north of Lajas, east of Hormigueros and Cabo Rojo, and west of Sabana Grande. San Germán is spread over eighteen barrios plus San Germán Pueblo. It is both a principal city of the San Germán–Cabo Rojo Metropolitan Statistical Area and the Mayagüez–San Germán–Cabo Rojo Combined Statistical Area. San Germán is the second oldest city of Puerto Rico, after San Juan, and its historic downtown is preserved as the San Germán Historic District.