Interstate 280 (I-280) is a 17.85-mile (28.73 km) Interstate Highway in the US state of New Jersey. It provides a spur from I-80 in Parsippany–Troy Hills, Morris County, east to Newark and I-95 in Kearny, Hudson County. In Kearny, access is provided toward the Holland Tunnel and Lincoln Tunnel to New York City. The western part of the route runs through suburban areas of Morris and Essex counties, crossing the Watchung Mountains. Upon reaching The Oranges, the setting becomes more urbanized and I-280 runs along a depressed alignment before ascending again in Newark. I-280 includes a vertical-lift bridge, the William A. Stickel Memorial Bridge, over the Passaic River between Newark and East Newark/Harrison. The highway is sometimes called the Essex Freeway. I-280 interchanges with several roads, including the Garden State Parkway in East Orange and Route 21 in Newark.

Essex County is located in the northeastern part of the U.S. state of New Jersey, and is one of the centrally located counties in the New York metropolitan area. As of the 2020 census, the county was the state's second-most populous county, with a population of 863,728, its highest decennial count since the 1970 census and an increase of 79,759 (+10.2%) from the 2010 census count of 783,969. The county is part of the North Jersey region of the state.