Interstate 295 (I-295) is a 52-mile-long (84 km) auxiliary Interstate Highway in the US state of Maine from I-95 in Scarborough to I-95 in West Gardiner. The highway was designated the Richard A. Coleman Highway in 2015 by the Maine Legislature. The highway serves as a bypass of Lewiston–Auburn and serves the Portland metropolitan area. It takes a more direct route between Portland and Augusta, the state capital, than its parent I-95. It also is toll-free, unlike I-95, which carries the tolled Maine Turnpike.

Interstate 95 (I-95) is a part of the Interstate Highway System that runs north–south from Miami, Florida to Houlton, Maine. The highway enters Maine from the New Hampshire state line in Kittery and runs for 303 miles (488 km) to the Canada–United States border at Houlton. It is the only primary Interstate Highway in Maine. In 2004, the highway's route between Portland and Gardiner was changed so that it encompasses the entire Maine Turnpike, a toll road running from Kittery to Augusta. As an Interstate Highway, all of I-95 in Maine is included in the National Highway System, a network of roads important to the country's economy, defense, and mobility.