Interstate 580 (I-580) is a 35.019-mile (56.358 km) auxiliary Interstate Highway in Western Nevada. It runs concurrently with US Route 395 (US 395) from an intersection with US 50 near the southern boundary of Carson City to the Reno Spaghetti Bowl interchange with I-80 in Reno. The freeway provides a high-speed direct route between Lake Tahoe and Carson City to Reno and I-80.

U.S. Route 395 (US 395) is an 85-mile-long (137 km) United States Numbered Highway near Lake Tahoe in the state of Nevada. It traverses the state after entering from California in Topaz Lake and crosses back into California near Hallelujah Junction. US 395 serves the cities of Gardnerville, Minden, Carson City and Reno. All of US 395 north of Carson City is a freeway and is built up to Interstate Highway standards. Part of the freeway section is also designated as Interstate 580 (I-580). US 395 is an important regional highway, serving the communities of Western Nevada, connecting them to other major communities via California, and it is the only major north–south arterial for the geographically isolated region.