Interstate 610 (I-610) is an auxiliary Interstate Highway that forms a 37.972-mile-long (61.110 km) loop around the inner city sector of the city of Houston, Texas. I-610, colloquially known as The Loop, Loop 610, The Inner Loop, or just 610, traditionally marks the border between the inner city of Houston and its surrounding areas. It is the innermost of the three Houston beltways, the other two being Beltway 8 and State Highway 99, of which various segments are under construction or planning. In Houston, the area inside I-610 is the urban core. Jeff Balke of the Houston Press wrote that the freeway "is as much a social and philosophical divide as a physical one". Mike Snyder in the Houston Chronicle wrote that, as someone from inside I-610, he historically felt "kind of special" due to being close to "the city's historical core and its major business, educational and cultural institutions".

Interstate 10 (I-10) is the major east–west Interstate Highway in the Southern United States. In the U.S. state of Texas, it runs east from Anthony, at the border with New Mexico, through El Paso, San Antonio, and Houston to the border with Louisiana in Orange. At just under 880 mi (1,420 km), the Texas segment of I-10, maintained by the Texas Department of Transportation, is the longest continuous untolled freeway in North America that is operated by a single authority. It is also the longest stretch of Interstate Highway with a single designation within a single state. Mile marker 880 and its corresponding exit number in Orange, Texas, are the highest-numbered mile marker and exit on any freeway in North America. Since widening was completed in 2008, a portion of the highway west of Houston is now also believed to be the widest in the world, at 26 lanes when including feeders.