Interstate 69 (I-69) is an Interstate Highway that is in the process of being built in the U.S. state of Texas. It is part of a longer I-69 extension known as the NAFTA superhighway, that, when completed, will connect Canada to Mexico. In Texas, it will connect Tenaha and the Louisiana segment of the route through the eastern part of the state and along the Texas Gulf Coast to Victoria, where it will split into three branches: I-69E to Brownsville, I-69C to Pharr, and I-69W to Laredo. The first segment of I-69 in Texas was opened in 2011 near Corpus Christi. The American Association of State Highway and Transportation Officials (AASHTO) approved an additional 58 miles (93 km) of U.S. Highway 77 (US 77) from Brownsville to the Willacy–Kenedy county line for designation as I-69, which was to be signed as I-69E upon concurrence from the Federal Highway Administration (FHWA). FHWA approval for this segment was announced on May 29, 2013. By March 2015, a 74.9-mile (120.5 km) section of US 59 had been completed and designated as I-69 through Greater Houston. As of 2024, short segments near the southern terminuses of the three branch routes have also all been completed. These branches are planned to be connected to the rest of the Interstate Highway System.

Interstate 610 (I-610) is an auxiliary Interstate Highway that forms a 37.972-mile-long (61.110 km) loop around the inner city sector of the city of Houston, Texas. I-610, colloquially known as The Loop, Loop 610, The Inner Loop, or just 610, traditionally marks the border between the inner city of Houston and its surrounding areas. It is the innermost of the three Houston beltways, the other two being Beltway 8 and State Highway 99, of which various segments are under construction or planning. In Houston, the area inside I-610 is the urban core. Jeff Balke of the Houston Press wrote that the freeway "is as much a social and philosophical divide as a physical one". Mike Snyder in the Houston Chronicle wrote that, as someone from inside I-610, he historically felt "kind of special" due to being close to "the city's historical core and its major business, educational and cultural institutions".