Interstate 70 (I-70) is a mainline route of the Interstate Highway System in the United States connecting Cove Fort, Utah, to Baltimore, Maryland. In the US state of Kansas, I-70 extends just over 424 miles (682 km) from the Colorado border near the town of Kanorado to the Missouri border in Kansas City. I-70 in Kansas contains the first segment in the country to start being paved and to be completed in the Interstate Highway System. The route passes through several of the state's principal cities in the process, including Kansas City, Topeka, and Salina. The route also passes through the cities of Lawrence, Junction City, and Abilene.

Lawrence is a city in and the county seat of Douglas County, Kansas, United States, and the sixth-largest city in the state. It is in the northeastern sector of the state, astride Interstate 70, between the Kansas and Wakarusa Rivers. As of the 2020 census, the population of the city was 94,934. Lawrence is a college town and the home to both the University of Kansas and Haskell Indian Nations University.