Interstate 75 (I-75) runs from near Williamsburg to Covington by way of Lexington in the US state of Kentucky. I-75 enters the Cumberland Plateau region from Tennessee, then descends into the Bluegrass region through the Pottsville Escarpment before crossing the Ohio River into Ohio. I-75 follows along the U.S. Route 25 (US 25) corridor for the entire length of Kentucky.

Georgetown is a home rule-class city in Scott County, Kentucky, United States. The population was 37,086 at the 2020 census. It is the 6th-largest city by population in the U.S. state of Kentucky. It is the seat of its county. It was originally called Lebanon when founded by Rev. Elijah Craig and was renamed in 1790 in honor of President George Washington. Historically, settlers were drawn to Georgetown for its Royal Spring.