Interstate 77 (I-77) is a part of the Interstate Highway System that runs from Columbia, South Carolina, to Cleveland, Ohio. In North Carolina, I-77 enters the state at Charlotte, from South Carolina. Crossing the Piedmont, it connects with Statesville before continuing north into Virginia. The landscapes traversed by I-77 is a contrast of urban and rural foothills, with views of the Blue Ridge Mountains seen from a distance on its most northern section. The Interstate extends for 105.7 miles (170.1 km) and has one auxiliary route.

Interstate 485 (I-485) is a 66.68-mile-long (107.31 km) auxiliary Interstate Highway encircling Charlotte, North Carolina. As a complete loop, it is primarily signed with "inner" and "outer" designations, though at some major interchanges, supplemental signage reflects the local compass orientation of the road. The entire route lies within Mecklenburg County.