Interstate 880 (I-880) is a north–south auxiliary Interstate Highway in the San Francisco Bay Area of Northern California. It runs from I-280 and State Route 17 (SR 17) in San Jose to I-80 and I-580 in Oakland, running parallel to the eastern shore of San Francisco Bay. For most of its route, I-880 is officially known as the Nimitz Freeway, after World War II fleet admiral Chester W. Nimitz, who retired to the Bay Area. The northernmost five miles (8.0 km) is also commonly referred to as the Cypress Freeway, after the former alignment of the freeway and its subsequent replacement.

Interstate 280 (I-280) is a 57.22-mile-long (92.09 km) major north–south auxiliary Interstate Highway in the San Francisco Bay Area of Northern California. It runs from I-680 and US Route 101 (US 101) in San Jose to King and 5th streets in San Francisco, running just to the west of the larger cities of San Francisco Peninsula for most of its route.