Interstate 88 (I-88) is an Interstate Highway located entirely within the US state of New York. Nominally signed as an east–west road as it has an even number, it extends for 117.75 miles (189.50 km) in a northeast–southwest direction from an interchange with I-81 north of the city of Binghamton to an interchange with the New York State Thruway (I-90) west of Schenectady. The freeway serves as an important connector route from the Capital District to Binghamton, Elmira, and Scranton, Pennsylvania. I-88 closely parallels NY 7, which was once the main route through the area.

New York State Route 7 (NY 7) is a 180.30-mile-long (290.16 km) state highway in New York in the United States. The highway runs from Pennsylvania Route 29 (PA 29) at the Pennsylvania state line south of Binghamton in Broome County, New York, to Vermont Route 9 (VT 9) at the Vermont state line east of Hoosick in Rensselaer County. Most of the road runs along the Susquehanna Valley, closely paralleling Interstate 88 (I-88) throughout that road's length. Portions of the highway route near the cities of Binghamton, Schenectady, and Troy date back to the early 19th century.