Interstate 95 (I-95) is part of the Interstate Highway System and runs from Miami, Florida, to the Canada–United States border near Houlton, Maine. In the US state of New York, I-95 extends 23.50 miles (37.82 km) from the George Washington Bridge in New York City to the Connecticut state line at Port Chester. The George Washington Bridge carries I-95 across the Hudson River from New Jersey into New York City. There, I-95 runs across Upper Manhattan on the Trans-Manhattan Expressway for 0.81 miles (1.30 km) through Washington Heights. It continues east across the Harlem River on the Alexander Hamilton Bridge and onto the Cross Bronx Expressway. In the Bronx, I-95 leaves the Cross Bronx at the Bruckner Interchange, joining the Bruckner Expressway to its end. North of the interchange with Pelham Parkway, it then continues northeast via the New England Thruway out of New York City into Westchester County and to the Connecticut state line, where I-95 continues on the Connecticut Turnpike.

The George Washington Bridge is a double-decked suspension bridge spanning the Hudson River, connecting Fort Lee in Bergen County, New Jersey, with the Washington Heights neighborhood of Manhattan in New York City. It is named after Founding Father George Washington, the first president of the United States. The George Washington Bridge is the world's busiest motor vehicle bridge, carrying a traffic volume of over 104 million vehicles in 2019, and is the world's only suspension bridge with 14 vehicular lanes.